Tobacco Leaf Extract Solanesol

Tobacco Leaf Extract Solanesol

Botanical Name:Nicotiana tabacum
Part Used:Leaf
Active ingredients:Solanesol
Appearance:White Powder
Specification:90% by HPLC
Package:25kg/drum
Storage: Stored in a cool, dry and dark place, shelf life 24 months.
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Description

What is Tobacco Leaf Extract Solanesol?

Solanesol, which mainly accumulates in solanaceous crops, including tobacco, tomato, potato, eggplant, and pepper plants, is a long-chain polyisoprenoid alcohol compound with nine isoprene units. Chemical synthesis of solanesol is difficult; therefore, solanesol is primarily extracted from solanaceous crops, particularly tobacco leaves. In plants, solanesol exists in both free and esterified forms, and its accumulation is influenced by genetic and environmental factors. Solanesol is widely used in the pharmaceutical industry as an intermediate for the synthesis of ubiquinone drugs, such as coenzyme Q10 and vitamin K2. Solanesol possesses antibacterial, antifungal, antiviral, anticancer, anti-inflammatory, and anti-ulcer activities, and solanesol derivatives also have anti-oxidant and antitumour activities, in addition to other bioactivities. Solanesol derivatives can also be used for the treatment of cardiovascular disease, osteoporosis, acquired immune deficiency syndrome, and wound healing. Solanesol biosynthesis occurs in plastids of higher plants via the 2-C-methyl-d-erythritol-4-phosphate (MEP) pathway. The key enzymes in solanesol biosynthesis, including 1-deoxy-d-xylulose-5-phosphate synthase, 1-deoxy-d-xylulose-5-phosphate-reductoisomerase, isopentenyl pyrophosphate isomerase, and solanesyl diphosphate synthase, are also important regulators of the MEP pathway, and their overexpression is favourable for downstream metabolic flow, further promoting the synthesis of downstream metabolites, such as solanesol. Future studies should determine the pharmacokinetic properties of solanesol and its derivatives and investigate the metabolic pathways and regulatory mechanisms mediating solanesol biosynthesis, metabolic and genetic engineering of solanesol, the synthetic biology of solanesol, and the physiological role of solanesol. In the present review, we systematically summarise current knowledge on solanesol resources, derivatives, bioactivities and medicinal applications, metabolic pathways, and key biosynthetic enzymes

Health Benefits of Tobacco Leaf Extract Solanesol

1.It can not only be used for synthesis of Coenzyme Q10 and Vitamin k2, but also for synthesis of raw materials as anti-allergic drug, anti-ulcer drug, hypolipidemic drug and anti-cancer drug.

2.In the field of medicine Coenzyme Q10 is commonly used for the prevention and treatment of cardiovascular system disease, and also has a certain treatment of acute cancer and virus hepatitis.

3.In addition, Coenzyme Q10 has strong healthcare effect to improve human immunity, maintain skin smoothness and enhance vitality as well.

 

Certificate of Analysis

ITEMSPECIFICATIONMETHODRESULT
AssaySolanesol 90%HPLCComplies
AppearenceWhite powderN/AComplies
Particle size100% pass 80 meshUSP32<786>Complies
Extract SolventsWater/EthanolN/AComplies
IdentificationPositive ReactionN/AComplies
Tests 
Loss on Drying≤5.0%Eur.Ph.6.0[2.8.17]Complies
Acid-insoluble ash≤7.0%Eur.Ph.6.0[2.4.16]Complies
Lead(Pb)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Arsenic(As)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Cadmium(Cd)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Mercury(Hg)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Solvents ResidueMeet Eur.Ph6.0<5.4>Eur.Ph 6.0<2.4.24>Complies
Pesticides ResidueNegativeUSP32<561>Complies
Microbiological Control
Total bacterial count≤1000cfu/gUSP30<61>Complies
Yeast & mold≤100cfu/gUSP30<61>Complies
SalmonellaNegativeUSP30<62>Complies
E.ColiNegativeUSP30<62>Complies

Flowchart of Production

plant extract flowchart

Package for Tobacco Leaf Extract Solanesol

herbal extract package

Shipping for Tobacco Leaf Extract Solanesol

  • By Express: Suitable for under 50kg, 5-10 days
  • By Air: Suitable for more than 50kg, 7-15 days
  • By Sea: Suitable for more than 500kg, 15-45days

Why Choose FYZ Tobacco Leaf Extract Solanesol?

  • FYZ is a professional GMP standard herbal extract manufacturer in China, provide OEM service.
  • FREE SAMPLE with freight collection (5-10g) for detection, if you need more, please contact us.
  • Fast delivery by DHL/FedEx,  air as your requirement.
  • All of our products from nature, no additive.
  • Money refund policy.

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