Polygonum Cuspidatum Extract Polydatin

Polygonum Cuspidatum Extract Polydatin

Botanical Name:Polygonum Cuspidatum
Part Used:Root
Active ingredients:Polydatin
Appearance: White Powder
Specification:98% by HPLC
Package:25kg/drum
Storage: Stored in a cool, dry and dark place, shelf life 24 months.
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Description

What is Polygonum Cuspidatum Extract Polydatin?

Polydatin, also known as piceid, is a glucoside of resveratrol, which means that the resveratrol is joined to a sugar molecule. It seems that in scientific documentations, scientists prefer to using piceid, while in supplements or daily life, polydatin is more popular. Therefore, we will use polydatin more often in the rest of the article.

Once the polydatin enters the bloodstream the sugar molecule is cleaved off, leaving the resveratrol. This in turn means that the glucoside of resveratrol is absorbed at a different rate to standard trans-resveratrol, thereby effectively increasing the half-life and the potency of the resveratrol.

Health Benefits of Polygonum Cuspidatum Extract Polydatin

1) lipid-lowering and lipid peroxidation

Polydatin can improve lipid membrane stability, significant inhibition of lipid peroxidation effect. Show that regulation of polydatin Hyperlipidemia rat serum lipid metabolism and rectify free radical metabolic disorder, which anti-atherosclerosis effect.

2) on vascular smooth muscle cells in vitro

Polydatin on rat vascular smooth muscle cells and effects of human umbilical arterial smooth muscle cells study: polydatin on intracellular calcium bi-directional regulation of PH value.

3) on myocardial cells in vitro

Reports on the study on myocardial cells in rats showed that cardiotonic effect may be achieved by increasing free calcium ion concentration in single cells and directly enhance myocardial contractility.

4) on platelet aggregation and microcirculation

Studies have found that polydatin in vitro and in vivo inhibition of arachidonic acid, adenosine diphosphate and epinephrine-induced platelet aggregation in rabbits, stronger than aspirin, indicating polydatin antithrombotic role is closely linked to strong anti-platelet aggregation.

5) antioxidant protective effect

Multiple organ failure caused by oxygen free radicals are an important mechanism, polydatin has significant antioxidant protection of the liver, inhibit the accumulation of lipid peroxidation in the liver of a class action.

Dosage of Polygonum Cuspidatum Extract Polydatin

There is no recommended dosage for pure polydatin (trans-resveratrol-3-O-glucoside). As we know, the dosage of revseratrol 98% is about 250mg to 500mg daily. We may conclude that the dose of polydatin is more or less the same as resveratrol dosing. One supplement formula suggests take 1 to 4 capsules of 500mg/capsule a day. High-dose of polydatin show overweight health benefits.

Potential Side Effects of Polygonum Cuspidatum Extract Polydatin

Polydatin is a rising ingredient used in dietary supplement, and no adverse effects have been reported yet.

Certificate of Analysis

ITEMSPECIFICATIONMETHODRESULT
AssayPolydatin 98%HPLCComplies
AppearenceWhite powderN/AComplies
Particle size100% pass 80 meshUSP32<786>Complies
Extract SolventsWater/EthanolN/AComplies
IdentificationPositive ReactionN/AComplies
Tests 
Loss on Drying≤5.0%Eur.Ph.6.0[2.8.17]Complies
Acid-insoluble ash≤7.0%Eur.Ph.6.0[2.4.16]Complies
Lead(Pb)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Arsenic(As)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Cadmium(Cd)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Mercury(Hg)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Solvents ResidueMeet Eur.Ph6.0<5.4>Eur.Ph 6.0<2.4.24>Complies
Pesticides ResidueNegativeUSP32<561>Complies
Microbiological Control
Total bacterial count≤1000cfu/gUSP30<61>Complies
Yeast & mold≤100cfu/gUSP30<61>Complies
SalmonellaNegativeUSP30<62>Complies
E.ColiNegativeUSP30<62>Complies

Flowchart of Production

plant extract flowchart

Package for Polygonum Cuspidatum Extract Polydatin

herbal extract package

Shipping for Polygonum Cuspidatum Extract Polydatin

  • By Express: Suitable for under 50kg, 5-10 days
  • By Air: Suitable for more than 50kg, 7-15 days
  • By Sea: Suitable for more than 500kg, 15-45days

Why Choose FYZ Polygonum Cuspidatum Extract Polydatin?

  • FYZ is a professional GMP standard herbal extract manufacturer in China, provide OEM service.
  • FREE SAMPLE with freight collection (5-10g) for detection, if you need more, please contact us.
  • Fast delivery by DHL/FedEx,  air as your requirement.
  • All of our products from nature, no additive.
  • Money refund policy.

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