Griffonia Simplicifolia Seed Extract 5-HTP

Botanical Name:Griffonia Simplicifolia
Part Used:Seed
Active ingredients:5-HTP
Appearance: White Powder
Specification:98% by HPLC
Storage: Stored in a cool, dry and dark place, shelf life 24 months.

What is Griffonia Simplicifolia Seed Extract 5-HTP?

Griffonia simplicifolia, an otherwise less than noteworthy shrub, has gained tremendous notoriety for its herbal seeds. The seeds contain 20 percent 5-Hydroxytryptophan, which has been argued to be a potentially effective treatment for a number of ailments, including depression, anxiety, migraines and even obesity. However, it also has links to the L-Tryptophan supplement, which has mostly been banned from sale in the U.S.

The plant is most commonly known for its seeds, which contain the amino acid 5-Hydroxytryptophan, or 5-HTP. This derivative of the amino acid tryptophan is produced naturally in the body from tryptophan. Tryptophan is found in high-protein foods, such as chicken, fish, beef and dairy products, although consuming these has not been shown to raise levels of 5-HTP by much. 5-HTP is converted into serotonin in the brain and central nervous system. Serotonin is a mood-altering chemical that is linked to healthy sleep patterns, balanced moods and appetite suppression.

Health Benefits of Griffonia Simplicifolia Seed Extract 5-HTP

5-HTP can help treat a variety of conditions linked to low levels of serotonin such as depression, insomnia and even obesity. If you would like to know more about the potential benefits of this impressive supplement then read on.

The weight loss potential of 5-HTP supplements is inextricably linked to its ability to increase the production of serotonin. Our modern lifestyles are thought to be at least partly responsible for low serotonin levels.

Low serotonin level cause an array of disorder such as anxiety, irritability, depression and obesity. This deficiency is exacerbated because worrying and anxiety causes the body to release serotonin which then needs replenishing.

Some studies have indicated that 5-HTP can help reduce weight in obese patients but why does it work?
When your serotonin levels are low, you are likely to crave carbohydrates and we know that carbs are the last thing you should be binging on when you are trying to control your weight.

Comfort eating of starchy and sugary foods is linked with periods of stress which of course results in weight gain but can also cause headache, fatigue and depression.
Several studies done over the past few decades have demonstrated that 5-HTP supplements can reduce carbohydrate cravings and appetite in general.

In one study significant weight loss was observed in obese patients given 5-HTP for a 6 week period. Despite not being prescribed a diet, participants who took 5-HTP ate fewer carbohydrates and experienced a reduced appetite.

The bottom line is that 5-HTP may help you to lose weight by reducing cravings for unhealthy fats and carbs and by satiating your appetite. However, like other diet supplements you are more likely to lose weight effectively when you take them in conjunction with a proper diet and exercise plan.

A deficiency in serotonin is linked strongly to depression and 5-HTP can in theory counteract this deficiency.

There is some evidence that 5-HTP could work just as well as antidepressant drugs for people with mild or moderate forms of depression. Like the prescription drugs Prozac or Zoloft, 5-HTP increases the body’s production of serotonin and its availability in the brain.

The way they work is different however. SSRIs like Prozac work by allowing the brain to reuse its existing serotonin while 5-HTP actually replenishes the brain’s serotonin levels.

One study which compared the effects of Luvox to 5-HTP found that it worked equally as well as the prescription drug. However, the studies done so far have been relatively small and researchers agree there is a need for larger scale trials to confirm its use.

Sleep disorders like insomnia are associated with many other problems like daytime fatigue, mood issues and even poor immunity. There is some evidence that 5-HTP may be useful in treating sleep deprivation. Because 5-HTP increases serotonin levels it also increases your melatonin levels which is a hormone linked to sleep cycles.

One study showed that people taking 5-HTP supplements fell asleep more quickly and slept better than those given a placebo.

Many people who suffer from fibromyalgia also have reduced levels of serotonin and they are sometimes prescribed antidepressant medication. According to research, 5-HTP supplementation can relieve many of the symptoms associated with fibromyalgia including anxiety, fatigue, pain and stiffness.

One study which involved 50 patients suffering from fibromyalgia found that 5-HTP significantly improved all of their primary symptoms.

Migraines and headaches are sometimes linked to low levels of serotonin and antidepressants are prescribed for some people with severe migraines.

Some studies indicate that 5-HTP taken in high doses can help treat migraines but other studies have showed they were no more effective than the placebo. As a result of this conflicting evidence, more research is necessary.

Dosage of Griffonia Simplicifolia Seed Extract 5-HTP

For depression: Several studies have used doses of 150-3000 mg daily in up to three divided doses for 2-6 weeks. Doses have also been gradually increased from 150 mg daily for 2 weeks up to 400 mg daily for 4 weeks.

Potential Side Effects of Griffonia Simplicifolia Seed Extract 5-HTP

5-HTP is POSSIBLY SAFE when taking by mouth appropriately. 5-HTP has been used safely in doses up to 400 mg daily for up to one year. However, some people who have taken it have developed a condition called eosinophilia-myalgia syndrome (EMS), a serious condition involving extreme muscle tenderness (myalgia) and blood abnormalities (eosinophilia). Some people think EMS might be caused by an accidental ingredient or contaminant in some 5-HTP products. However, there is not enough scientific evidence to know if EMS is caused by 5-HTP, a contaminant, or some other factor. Until more is known, 5-HTP should be used cautiously.

Other potential side effects of 5-HTP include heartburn, stomach pain, nausea, vomiting, diarrhea, drowsiness, sexual problems, and muscle problems.

5-HTP is POSSIBLY UNSAFE when taken by mouth in large doses. Doses from 6-10 grams daily have been linked to severe stomach problems and muscle spasms.

Certificate of Analysis

Assay5-HTP 98%HPLCComplies
AppearenceWhite powderN/AComplies
Particle size100% pass 80 meshUSP32<786>Complies
Extract SolventsWater/EthanolN/AComplies
IdentificationPositive ReactionN/AComplies
Loss on Drying≤5.0%Eur.Ph.6.0[2.8.17]Complies
Acid-insoluble ash≤7.0%Eur.Ph.6.0[2.4.16]Complies
Solvents ResidueMeet Eur.Ph6.0<5.4>Eur.Ph 6.0<2.4.24>Complies
Pesticides ResidueNegativeUSP32<561>Complies
Microbiological Control
Total bacterial count≤1000cfu/gUSP30<61>Complies
Yeast & mold≤100cfu/gUSP30<61>Complies

Flowchart of Production

plant extract flowchart

Package for Griffonia Simplicifolia Seed Extract 5-HTP

herbal extract package

Shipping for Griffonia Simplicifolia Seed Extract 5-HTP

  • By Express: Suitable for under 50kg, 5-10 days
  • By Air: Suitable for more than 50kg, 7-15 days
  • By Sea: Suitable for more than 500kg, 15-45days

Why Choose FYZ Griffonia Simplicifolia Seed Extract 5-HTP?

  • FYZ is a professional GMP standard herbal extract manufacturer in China, provide OEM service.
  • FREE SAMPLE with freight collection (5-10g) for detection, if you need more, please contact us.
  • Fast delivery by DHL/FedEx,  air as your requirement.
  • All of our products from nature, no additive.
  • Money refund policy.



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