Codonopsis Extract Polysaccharide

Codonopsis Extract Polysaccharide

Botanical Name:Codonopsis Pilosula
Part Used:Root
Active ingredients:Saponins, polysaccharide
Appearance: Brown Powder
Storage: Stored in a cool, dry and dark place, shelf life 24 months.


What is Codonopsis Extract?

Codonopsis is a genus of flowering plant in the family Campanulaceae. As currently recognized, Codonopsis includes two other groups sometimes separated as distinct genera, i.e. Campanumoea and Leptocodon. The enlarged genus Codonopsis is widespread across eastern, southern, central, and southeastern Asia, including China, Japan, the Russian Far East, Kazakhstan, the Indian Subcontinent, Iran, Indochina, Indonesia, etc.

Health Benefits of Codonopsis Extract

Codonopsis has many benefits and has been used as food or herb by Asian countries for countless centuries. Although Western medicine was adamantly doubtful about the health benefits of many plants and herbs used in Asia, the good news is that the science is starting to catch up.  There have been some studies done recently that have shown that this plant has plenty of health benefits.

1. Inflammation

There is some evidence suggesting that C. pilosula may reduce inflammation. According to a 2014 investigation issued in the Journal of Natural Medicines, C. pilosula contains triterpenoids that contribute to the anti-inflammatory activity of codonopsis extract. The methanol extracts of C. pilosula barred the production of nitric oxide and TNF-alpha (tumor necrosis factor-alpha), phagocytic uptake in LPS –activated RAW264.7 cells. Thus, the anti-inflammation mechanism of the C. pilosula involves suppressing cellular responses of macrophages and monocytes by preventing the IKK/NF-KB pathway and redox activation.

Another 2009 research printed in the Archives of Pharmacal Research found that the codonopsis extract contained saponins that also offer anti-inflammatory benefits. This study showed that codonopsis enhances the inflammatory response of some cells in the immune system and suppresses the tumor necrosis factor and nitric oxide. Although the results of the study show that the plant should be given consideration as an herbal medicine with potent anti-inflammatory effects, more studies should be done to verify the science behind it.

2. Diabetes

C. pilosula/C. lanceolata is one of the traditional Chinese medicinal herbs used in treating diabetes and reducing the complications that arise from diabetes. In a 2011 study issued in the Journal of Ethnopharmacology, traditional Chinese medicinal herbs sparked great interest because they may be vital for treating severe chronic diseases like diabetes while producing fewer side effects than most conventional medications. They also cost less and provide better patient tolerance than pharmaceutical drugs. According to this study, C. pilosula lowers blood glucose significantly.

3. Brain Boost

C. pilosula combined with ginkgo biloba (G. biloba) enhances memory and learning better than using gingko biloba only. These were the results of a 2004 study published in the Alternative Therapies in Health and Medicine to determine the usefulness of several Chinese herbs used both for acquisition and retention singly or in combination. The results of the test showed that combining C. pilosula with G. biloba produced better results than G. biloba alone. In this study, the subjects were given 75mg of C. pilosula and 40mg of Ginkgo biloba extract.

4. Fatty Liver

Codonopsis lanceolata may help protect individuals against fatty liver. This information was published in 2009 in the Journal of Medicinal Food. These results are important because alcohol is the primary cause of fatty liver in the world. This study was done on rats, and more research needs to be done to see if the results apply to humans as well.

The codonopsis extract has vital functions too, and it has been used from the ancient days until today. The benefits of codonopsis root include cleansing the lungs and improving the functioning of the digestive system.

5. Adaptogen

Similar to other adaptogens, C. pilosula is used for stress reduction and improving the ability to cope with stress. An adaptogen is a substance that is meant to help you cope better with both mental and physical stress by returning your body to homeostasis. Adaptogens such as codonopsis pilosula and ginseng are often used in Chinese traditional medicine. However, western medicine has yet to verify adaptogens really work as well as Chinese traditional medicine purports.

Dosage of Codonopsis Extract

There is no proven safe or effective dose for adults. Traditionally, 3-9 grams of codonopsis decoction has been used; some conditions may require dosages up to 30 grams per day.

Potential Side Effects Of Codonopsis Extract

Codonopsis is POSSIBLY SAFE for most people when taken by mouth in appropriate amounts.
Special Precautions & Warnings:

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking codonopsis if you are pregnant or breast-feeding. Stay on the safe side and avoid use.

Bleeding disorders: Codonopsis might slow blood clotting and increase bleeding. In theory, taking codonopsis might make bleeding disorders worse.

Surgery: Codonopsis might slow blood clotting. In theory, taking codonopsis might increase the risk for bleeding during and after surgical procedures. Stop using codonopsis at least two weeks before a scheduled surgery.

Certificate of Analysis

Appearence Brown powderN/AComplies
Particle size100% pass 80 meshUSP32<786>Complies
Extract SolventsWater/EthanolN/AComplies
IdentificationPositive ReactionN/AComplies
Loss on Drying≤5.0%Eur.Ph.6.0[2.8.17]Complies
Acid-insoluble ash≤7.0%Eur.Ph.6.0[2.4.16]Complies
Solvents ResidueMeet Eur.Ph6.0<5.4>Eur.Ph 6.0<2.4.24>Complies
Pesticides ResidueNegativeUSP32<561>Complies
Microbiological Control
Total bacterial count≤1000cfu/gUSP30<61>Complies
Yeast & mold≤100cfu/gUSP30<61>Complies

Flowchart of Production

plant extract flowchart

Package for Codonopsis Extract Polysaccharide

herbal extract package

Shipping for Codonopsis Extract Polysaccharide

  • By Express: Suitable for under 50kg, 5-10 days
  • By Air: Suitable for more than 50kg, 7-15 days
  • By Sea: Suitable for more than 500kg, 15-45days

Why Choose FYZ Codonopsis Extract Polysaccharide?

  • FYZ is a professional GMP standard herbal extract manufacturer in China, provide OEM service.
  • FREE SAMPLE with freight collection (5-10g) for detection, if you need more, please contact us.
  • Fast delivery by DHL/FedEx,  air as your requirement.
  • All of our products from nature, no additive.
  • Money refund policy.


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