Celery Seed Extract Apigenin

Celery Seed Extract Apigenin

Botanical Name:Apium graveolens
Part Used:Seed
Active ingredients:Apigenin
Appearance:Yellow crystalline powder
Specification:98% by HPLC, 10:1, 20:1
Package:25kg/drum
Storage: Stored in a cool, dry and dark place, shelf life 24 months.
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Description

What is Celery Seed Extract?

Celery, which has the scientific name Apium graveolens, is a vegetable in the plant family called Apiaceae. The benefits of celery begin with it being an excellent source of antioxidants and beneficial enzymes, in addition to vitamins and minerals such as vitamin K, vitamin C, potassium, folate and vitamin B6.

Administered as an anti-hypertensive agent in folk medicine for centuries, celery continues to prove that there are many cardiovascular benefits. In recent pharmacological studies, celery demonstrates both antioxidant and anti-inflammatory activities that help improve blood pressure and cholesterol levels, as well as prevent heart disease.

Celery also provides dietary fiber – especially when you eat more than one cup at a time – that boosts digestion and weight loss. In addition, celery’s high percentage of water and electrolytes can prevent dehydration, and special compounds help celery to act as a diuretic and reduce bloating. As a supplier of antioxidant flavonoids and polyphenol phytonutrients, other significant benefits of celery include its ability to improve liver, skin, eye and cognitive health.

Health Benefits of Celery Seed Extract

1. Helps Lower High Cholesterol

Benefits of celery include its cholesterol-lowering power that make it useful for improving or maintaining heart health. Celery contains a unique compound called  3-n-butylphthalide (BuPh) that has previously been reported to have lipid-lowering action, but researchers believe celery has many other other beneficial compounds that are still emerging in research.

In a study conducted by the Department of Pharmacology at the University of Singapore, when rats were fed a high-fat diet for eight weeks, rats that had been given celery seed extract showed significantly lower levels of lipids in their blood compared to the control group of rats that didn’t receive celery seed extract.

The group supplementing with celery seed extract experienced a beneficial reduction in serum total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and triglyceride (TG) concentrations.

2. Lowers Inflammation

Celery contains antioxidants and polysaccharides that are known to act as anti-inflammatories, especially flavonoid and polyphenol antioxidants. These support overall health, especially as someone ages, by fighting free-radical damage (or oxidative stress) that can lead to inflammation. Inflammation is often a contributing cause of chronic diseases like cancer, heart disease, arthritis and many more.

Researchers have identified over a dozen different types of antioxidants that are responsible for the benefits of celery — these include such phenolic acids as caffeic acid and ferulic acid, plus flavaols like quecetin. This makes celery useful for treating a wide range of conditions that are made worse by inflammation: joint pain (such as from arthritis), gout, kidney and liver infections, skin disorders, irritable bowel syndrome and urinary tract infections, just to name a few.

 3. Helps Prevent or Treat High Blood Pressure

Celery seed extracts have anti-hypertensive properties that help reduce high blood pressure, one of the important risk factors for coronary heart disease that is the largest cause of mortality in industrial countries.

Benefits of celery seeds include potentially helping to control chronic elevated blood pressure levels. The blood pressure-lowering benefits of celery come from its seeds, which contain hexanic, methanolic, and aqueous-ethanolic extracts that improve circulation, lower inflammation and help control blood pressure.

When rats were given celery seed extract over a seven-week period, they experienced significant improvements in blood pressure levels compared to rats being fed the same diet but not receiving celery seed extract. It’s believed that celery helps lower high blood pressure by acting as a smooth muscle relaxant and improving the flow of calcium and potassium into and out of cells. Celery seed extract helps blood vessels to expand and contract, improve blood flow, and aid in overall heart health.

 4. Helps Prevent Ulcers

Here’s one of the benefits of celery you may not have known about: It can help prevent or reduce the formation of painful ulcers. A 2010 study published in the Journal of Pharmaceutical Biology found that celery contains a special type of ethanol extract that is useful in protecting the lining of the digestive tract from ulcers. Celery seed extract has the ability to significantly replenish depleted levels of gastric mucus that is needed in the stomach lining to prevent tiny holes and openings from forming.

Researchers believe celery nourishes the stomach, colon and intestines due to the presence of chemical constituents such as flavonoids, tannins, volatile oils and alkaloids that control the level of gastric acid released while also improving the level of protective mucus.

5. Protects Liver Health

When researchers from the Department of Nutrition and Food Science at Helwan University in Egypt fed rats celery (along with chicory and barley), these rats experienced a reduction in the amount of dangerous fat buildup within the liver.

Precisely, when researchers supplemented the high-cholesterol diets of rats with celery, chicory and barley powder, they observed an improvement in liver enzyme function and blood lipid levels. The more celery, chicory and barley the rats were given, the more their liver health improved. This suggests that a diet high in celery, as well as chicory and barley, can be beneficial for people suffering from liver disease.

6. Beneficial for Weight Loss

Celery is extremely low in calories and can be a valuable food to help you lose weight because of its ability to provide vital nutrients and to help regulate lipid (fat) metabolism. One of the major benefits of celery is that it’s so nutrient-dense, meaning it provides antioxidants, electrolytes, vitamins and minerals like vitamin C, B vitamins and potassium – all with very little calories.

7. Boosts Digestion and Reduces Bloating

Celery seeds contain an odorless and oily compound known as NBP that has a diuretic effect and helps the body to detox. In studies involving rats, urine volume was significantly greater when rats were given celery seed extract compared to a control group.

The digestive benefits of celery are partly due to its diuretic effect. This could also be one of the possible anti-hypertensive mechanisms of celery seeds that helps to lower blood pressure. Because it improves circulation within the intestines, it’s also useful for improving digestion by helping to relieve bloating and puffiness from water retention.

8. Contains Anti-Microbial Properties That Fight Infections

Celery seeds have actually been used for centuries as an herbal medicine with reported antibacterial effects. A 2009 report published in the Journal of Pharmacy and Pharmacology shows that celery contains special anti-microbial components found in the seeds of the celery plant.

When extract was taken from celery seeds and combined with harmful bacteria compounds that cause infection in humans, the celery seed extract was able to significantly purify and reduce the bacteria’s growth, suggesting celery can be used to naturally boost immunity and fight bacterial infections.

9. Helps Prevent Urinary Tract Infections

Because celery helps to reduce uric acid and stimulates urine production, it’s beneficial for fighting bacterial infections within the digestive tract and reproductive organs. Similarly to cranberries that are known for fighting urinary tract infections (UTIs), celery can help prevent such UTIs, as well as bladder disorders, kidney problems and possibly even cysts on reproductive organs.

10. May Help Protect from Cancer

Another one of the important benefits of celery? It’s in the same plant family as cancer-protective vegetables like carrots, celery, fennel, parsley and parsnips, which all contain chemo-protective compounds called polyacetylenes. Early studies have shown that polyacetylenes help reduce toxicity and fight against cancer formation, specifically breast cancer, intestinal cancer and leukemia.

Polyacetlynes have many immune-boosting effects, including tumor-fighting abilities that stop mutated cells from proliferating. According to faculty of the Department of Agricultural Sciences at the Aarhus University of Denmark, “polyacetylenes have shown many interesting bioactivities including anti-inflammatory, antiplatelet-aggregatory, cytotoxic, antitumor activity, as well as activity against bacteria and mycoplasma.”

Dosage of Celery Seed Extract

Many Celery seed Extract 10:1 powder supplements recommend a dosage of around 500 mg to 1500 mg.

Potential Side Effects Of Celery Seed Extract Apigenin

Celery oil and celery seeds are LIKELY SAFE when taken by mouth in food amounts. Celery is POSSIBLY SAFE for most people when taken by mouth or applied to the skin in medicinal amounts for a short period of time. However, it may cause skin inflammation and sensitivity to the sun.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Celery oil and celery seeds are LIKELY UNSAFE when taken by mouth in medicinal amounts during pregnancy. Large amounts of celery might make the uterus contract and cause a miscarriage. There is not enough reliable information about the safety of taking celery oil and seeds if you are breast-feeding. Stay on the safe side and avoid use.

Allergies: Celery can cause allergic reactions in people who are sensitive to certain other plants and spices including wild carrot, mugwort, birch, and dandelion. This has been called the “celery-carrot-mugwort-spice syndrome.”

Bleeding disorder: There is concern that celery might increase the risk of bleeding when used in medicinal amounts. Don’t use celery if you have a bleeding disorder.

Kidney problems: Don’t use celery in medicinal amounts if you have kidney problems. Celery seed extract might cause inflammation.

Low blood pressure: Celery seed extract in medicinal amounts might lower blood pressure. If your blood pressure is already low, taking celery might make it drop too much.

Surgery: Celery can affect the central nervous system. There is some concern that celery, in combination with anesthesia and other medications used during and after surgery might slow down the central nervous system too much. Stop using celery at least 2 weeks before a scheduled surgery.

Certificate of Analysis

ITEMSPECIFICATIONMETHODRESULT
AssayApigenin 98%, 10:1HPLC, TLCComplies
AppearenceYellow crystalline powderN/AComplies
Particle size100% pass 80 meshUSP32<786>Complies
Extract SolventsWater/EthanolN/AComplies
IdentificationPositive ReactionN/AComplies
Tests 
Loss on Drying≤5.0%Eur.Ph.6.0[2.8.17]Complies
Acid-insoluble ash≤7.0%Eur.Ph.6.0[2.4.16]Complies
Lead(Pb)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Arsenic(As)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Cadmium(Cd)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Mercury(Hg)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Solvents ResidueMeet Eur.Ph6.0<5.4>Eur.Ph 6.0<2.4.24>Complies
Pesticides ResidueNegativeUSP32<561>Complies
Microbiological Control
Total bacterial count≤1000cfu/gUSP30<61>Complies
Yeast & mold≤100cfu/gUSP30<61>Complies
SalmonellaNegativeUSP30<62>Complies
E.ColiNegativeUSP30<62>Complies

Flowchart of Production

plant extract flowchart

Package for Celery Seed Extract Apigenin

herbal extract package

Shipping for Celery Seed Extract Apigenin

  • By Express: Suitable for under 50kg, 5-10 days
  • By Air: Suitable for more than 50kg, 7-15 days
  • By Sea: Suitable for more than 500kg, 15-45days

Why Choose FYZ Celery Seed Extract Apigenin?

  • FYZ is a professional GMP standard herbal extract manufacturer in China, provide OEM service.
  • FREE SAMPLE with freight collection (5-10g) for detection, if you need more, please contact us.
  • Fast delivery by DHL/FedEx,  air as your requirement.
  • All of our products from nature, no additive.
  • Money refund policy.

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