Bupleurum Falcatum Extract Saikosaponins

Bupleurum Falcatum Extract Saikosaponins

Botanical Name:Bupleurum falcatum L.
Part Used:Root
Active ingredients:Saikosaponins
Appearance:Yellowish brown powder
Specification:5% by UV, 10:1
Package:25kg/drum
Storage: Stored in a cool, dry and dark place, shelf life 24 months.
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Description

What is Bupleurum Falcatum Extract?

Bupleurum Falcatum is a perennial herb that grows mainly in China, but also is cultivated in other areas. The plant grows to approximately 1 m in height and requires abundant sun to flourish. The leaves are long and sickle-shaped with parallel veining. Terminal clusters of small, yellow flowers appear in autumn. The long cone or column-shaped, single or branched root is 10 to 20 cm in length and 0.5 to 1.5 cm in diameter. It is light brown to brown, may be wrinkled, and is easily broken.

Health Benefits of Bupleurum Falcatum Extract Saikosaponins

1. Improves General Liver Function and Detoxification

The liver is the largest internal organ in our bodies and is responsible for many vital tasks, including getting rid of and neutralizing all kinds of toxins. The liver also makes bile, which helps the body absorb and properly utilize fats and fat-soluble vitamins.

Keeping the liver working as it should is key to anyone and everyone’s good health. There are many habits and environmental factors that take a toll on the liver, including drinking alcohol, eating processed foods, taking certain medications and pollution. This herb is best known for its ability to detoxify the liver and improve overall liver health. It’s definitely one of the top powerful herbal remedies for liver function, which includes properly converting nutrients and removing hazardous toxins.

2. Prevents and Treats Cirrhosis and Liver Cancer

Cirrhosis is a slowly progressing disease of the liver in which healthy liver tissue is replaced with scar tissue that blocks blood and bile flow through the liver and keeps it from working properly. The most common causes of cirrhosis are excessive alcohol consumption as well as chronic infection with the hepatitis C virus. If the disease is severe enough, it can be fatal.

Sho-saiko-to, or Xiao Chai Hu Tang, is a Japanese medicine that includes bupleurum. Laboratory and animal studies conducted at Osaka City University Medical School in Japan suggest that Sho-saiko-to has a protective effect on the liver. One study showed that this herbal formula helped prevent the development of hepatocellular carcinomas (liver cancer) in patients who already have cirrhosis. This is huge when you consider that the incidence of liver cancer is extremely high in cirrhosis patients.

3. Boosts Adrenal Gland Function

Bupleurum has been used in combination with licorice and panax ginseng to aid and stimulate adrenal gland function. This has been especially helpful for patients with a history of long-term use of corticosteroid drugs, which take a major toll on adrenal health. By aiding the adrenal glands, bupleurum can help harmonize the body and improve energy levels by combatting adrenal insufficiency.

4. Relieves Epilepsy Episodes

Another surprising yet awesome finding is bupleurum’s potential to help epilepsy sufferers. Epilepsy is disorder in which nerve cell activity in the brain is disturbed, causing seizures. Bupleurum is included in two similar Chinese herbal formulas, Sho-saiko-to and Saiko-keishi-to, which contain the same herbs but in different ratios. Other ingredients in these two formulas include cassia bark, ginger root, peony root, pinellia root, jujube fruit, Asian ginseng root, Asian skullcap root and licorice root.

Preliminary trials have demonstrated that both herbal formulas could offer relief to epilepsy patients. The trials also showed that there were zero negative interactions with a variety of anticonvulsant drugs already being taken by the subjects at the time of the study.

5. Fights Ovarian Cancer

The goal of one 2015 study conducted by the Department of Traditional Chinese Medicine at the Military General Hospital of Beijing PLA in China was to  evaluate the anticancer, apoptotic and antioxidant properties of Bupleurum chinense root extract against human epithelial ovarian cancer cells in vitro. The results showed that the extract was able to induce impressively strong and dose-dependent cancer-killing effects on ovarian cancer cells. The extract also showed its ability to encouraged cancer cell shrinkage.

Overall, the anticancer effects of the extract were attributed to its ability to foster the programmed cell death of cancer cells, DNA fragmentation (a characteristic of apoptosis or programmed cell death) and a disruption of energy metabolism of cancer cells. Given its results in fighting ovarian and liver cancers, this herb holds the potential to be a tremendous natural cancer treatment.

6. Treats Depression Due to PMS or Menopause

Many people today take mood-stabilizing drugs for their anxiety or depression. Most of these are selective serotonin re-uptake inhibiter). These drugs don’t come without their own very concerning side effects so it’s always worthwhile to look into the possibility of natural remedies.

Traditional Chinese Medicine believes that liver qi stagnation is the central cause of depression. Practitioners of TCM often recommend Chai hu shu gan san, an herbal formula that includes bupleurum, for stagnation of liver qi (energy that flows in the body). Chai hu shu gan san has been found to be especially effective when it’s used to treat the depression that can often occur during premenstrual syndrome (PMS) as well as menopause.

Dosage of Bupleurum Falcatum Extract Saikosaponins

The most commonly recommended therapeutic dosage for Bupleurum is 3,000 – 4,000 mg per day and the usual therapeutic dosage of 1:1 fluid Bupleurum Falcatum extract is 3 – 4 ml per day. Studies have found that short and long term consumption is beneficial for the treatment of all of the benefits listed above. Doses of up to 10 grams have been taken for extended periods of time (months) without adverse effects. It has been traditionally prescribed at this dose however; as Western herbs contained concentrated (standardised) components, it is prudent not to exceed 4g per day.

Potential Side Effects Of Bupleurum Falcatum Extract

There is no conclusive report yet on the possible side effects and contraindications associated with the use of bupleurum falcatum extract. Some reported side effects include increased bowel movements, intestinal gas and drowsiness. When taken in combination with other herbs, it has caused serious lung and breathing problems for some users.

Avoid this herb if you’re pregnant or nursing. It’s also not recommended if you have a bleeding disorder, diabetes or an autoimmune disease.

Stop taking this herb at least two weeks before undergoing surgery because it can increase your risk of bleeding.

Since bupleurum can increase immune system activity, it might decrease the effectiveness of immunosuppressant drugs. Speak with your doctor before taking this herb or any others if you currently take an immunosuppressant or any other medications, or if you have any ongoing health concerns.

Certificate of Analysis

ITEMSPECIFICATIONMETHODRESULT
AssaySaikosaponins 5%UVComplies
AppearenceYellowish brown powderN/AComplies
Particle size100% pass 80 meshUSP32<786>Complies
Extract SolventsWater/EthanolN/AComplies
IdentificationPositive ReactionN/AComplies
Tests 
Loss on Drying≤5.0%Eur.Ph.6.0[2.8.17]Complies
Acid-insoluble ash≤7.0%Eur.Ph.6.0[2.4.16]Complies
Lead(Pb)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Arsenic(As)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Cadmium(Cd)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Mercury(Hg)≤1.0mg/kgEur.Ph6.0<2.2.58>ICP-MSComplies
Solvents ResidueMeet Eur.Ph6.0<5.4>Eur.Ph 6.0<2.4.24>Complies
Pesticides ResidueNegativeUSP32<561>Complies
Microbiological Control
Total bacterial count≤1000cfu/gUSP30<61>Complies
Yeast & mold≤100cfu/gUSP30<61>Complies
SalmonellaNegativeUSP30<62>Complies
E.ColiNegativeUSP30<62>Complies

Flowchart of Production

plant extract flowchart

Package for Bupleurum Falcatum Extract Saikosaponins

herbal extract package

Shipping for Bupleurum Falcatum Extract Saikosaponins

  • By Express: Suitable for under 50kg, 5-10 days
  • By Air: Suitable for more than 50kg, 7-15 days
  • By Sea: Suitable for more than 500kg, 15-45days

Why Choose FYZ Bupleurum Falcatum Extract Saikosaponins?

  • FYZ is a professional GMP standard herbal extract manufacturer in China, provide OEM service.
  • FREE SAMPLE with freight collection (5-10g) for detection, if you need more, please contact us.
  • Fast delivery by DHL/FedEx,  air as your requirement.
  • All of our products from nature, no additive.
  • Money refund policy.

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